NTAN1 antibody (AA 1-310)

Catalog No. ABIN7268787

This anti-NTAN1 antibody is a Rabbit Polyclonal antibody detecting NTAN1 in WB. Suitable for Human.

Quick Overview for NTAN1 antibody (AA 1-310) (ABIN7268787)

Target: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NTAN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NTAN1 Antibody

Binding Specificity: AA 1-310

Purpose: NTAN1 Rabbit pAb

Sequence: MPLLVEGRRV RLPQSAGDLV RAHPPLEERA RLLRGQSVQQ VGPQGLLYVQ QRELAVTSPK DGSISILGSD DATTCHIVVL RHTGNGATCL THCDGTDTKA EVPLIMNSIK SFSDHAQCGR LEVHLVGGFS DDRQLSQKLT HQLLSEFDRQ EDDIHLVTLC VTELNDREEN ENHFPVIYGI AVNIKTAEIY RASFQDRGPE EQLRAARTLA GGPMISIYDA ETEQLRIGPY SWTPFPHVDF WLHQDDKQIL ENLSTSPLAE PPHFVEHIRS TLMFLKKHPS PAHTLFSGNK ALLYKKNEDG LWEKISSPGS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human NTAN1 (NP_775745.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NTAN1

Target: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Alternative Name: NTAN1

Background: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.,NTAN1,PNAA,PNAD,Cell Biology & Developmental Biology,Ubiquitin,NTAN1

Molecular Weight: 34kDa

Gene ID: 123803

UniProt: Q96AB6