UNC5B antibody (AA 290-377)

Catalog No. ABIN7268854

This Rabbit Polyclonal antibody specifically detects UNC5B in WB and IF. It exhibits reactivity toward Human.

Quick Overview for UNC5B antibody (AA 290-377) (ABIN7268854)

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC5B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-UNC5B Antibody

Binding Specificity: AA 290-377

Purpose: UNC5B Rabbit pAb

Sequence: FQKTACTTIC PVDGAWTEWS KWSACSTECA HWRSRECMAP PPQNGGRDCS GTLLDSKNCT DGLCMQNKKT LSDPNSHLLE ASGDAALY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 290-377 of human UNC5B (NP_734465.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UNC5B

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Alternative Name: UNC5B

Background: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.,UNC5B,UNC5H2,p53RDL1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Cardiovascular,UNC5B

Molecular Weight: 102kDa/103kDa

Gene ID: 219699

UniProt: Q8IZJ1