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TRKA antibody (C-Term)

NTRK1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7268895
  • Target See all TRKA (NTRK1) Antibodies
    TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
    Binding Specificity
    • 40
    • 20
    • 19
    • 18
    • 16
    • 15
    • 15
    • 11
    • 11
    • 8
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 224
    • 145
    • 134
    • 15
    • 3
    • 3
    • 1
    • 1
    Human
    Host
    • 237
    • 14
    • 3
    • 2
    • 1
    Rabbit
    Clonality
    • 231
    • 25
    • 1
    Polyclonal
    Conjugate
    • 97
    • 17
    • 14
    • 12
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRKA antibody is un-conjugated
    Application
    • 176
    • 96
    • 79
    • 78
    • 49
    • 38
    • 29
    • 18
    • 17
    • 14
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Purpose
    TrkA Rabbit pAb
    Sequence
    LYRKFTTESD VWSFGVVLWE IFTYGKQPWY QLSNTEAIDC ITQGRELERP RACPPEVYAI MRGCWQREPQ QRHSIKDVHA RLQALAQAPP VYLDVLG
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human TrkA (NP_002520.2).
    Isotype
    IgG
    Top Product
    Discover our top product NTRK1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
    Alternative Name
    NTRK1 (NTRK1 Products)
    Background
    This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.,NTRK1,MTC,TRK,TRK1,TRKA,Trk-A,p140-TrkA,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Neuroscience,NTRK1
    Molecular Weight
    77kDa/83kDa/86kDa/87kDa
    Gene ID
    4914
    UniProt
    P04629
    Pathways
    RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process
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