NMNAT1 antibody (AA 1-150)

Catalog No. ABIN7268909

The Rabbit Polyclonal anti-NMNAT1 antibody is suitable to detect NMNAT1 in samples from Human. It has been validated for WB.

Quick Overview for NMNAT1 antibody (AA 1-150) (ABIN7268909)

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMNAT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NMNAT1 Antibody

Binding Specificity: AA 1-150

Purpose: NMNAT1 Rabbit pAb

Sequence: MENSEKTEVV LLACGSFNPI TNMHLRLFEL AKDYMNGTGR YTVVKGIISP VGDAYKKKGL IPAYHRVIMA ELATKNSKWV EVDTWESLQK EWKETLKVLR HHQEKLEASD CDHQQNSPTL ERPGRKRKWT ETQDSSQKKS LEPKTKAVPK

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human NMNAT1 (NP_073624.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NMNAT1

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Alternative Name: NMNAT1

Background: This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15.,NMNAT1,LCA9,NMNAT,PNAT1,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,NMNAT1

Molecular Weight: 31kDa

Gene ID: 64802

UniProt: Q9HAN9