NRF1 antibody

Catalog No. ABIN7269022

This Rabbit Monoclonal antibody specifically detects NRF1 in WB, IHC, IP and ChIP. It exhibits reactivity toward Human.

Quick Overview for NRF1 antibody (ABIN7269022)

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NRF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Product Details anti-NRF1 Antibody

Purpose: NRF1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human NRF1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000, IHC,1:50 - 1:200,IP,1:50 - 1:200,ChIP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NRF1

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Alternative Name: NRF1

Background: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014],ALPHA-PAL,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial Biogenesis,Neurodegenerative Diseases,Neuroscience,Nucleotide metabolism,Nucleotide metabolism_Molecular processes,Transcription Factors,NRF1

Molecular Weight: 68kDa

Gene ID: 4899

UniProt: Q16656

Pathways: Regulation of Lipid Metabolism by PPARalpha