OPRD1 antibody
Quick Overview for OPRD1 antibody (ABIN7269100)
Target
See all OPRD1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Purpose
- OPRD1 Rabbit mAb
-
Cross-Reactivity
- Human, Mouse, Rat
-
Characteristics
- Monoclonal Antibodies
-
Purification
- Affinity purification
-
Immunogen
- A synthesized peptide derived from human OPRD1
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB,1:500 - 1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- OPRD1 (Opioid Receptor, delta 1 (OPRD1))
-
Alternative Name
- OPRD1
-
Background
- G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.,OPRD,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Neuroscience,Signal Transduction,OPRD1
-
Molecular Weight
- 40kDa
-
Gene ID
- 4985
-
UniProt
- P41143
-
Pathways
- Protein targeting to Nucleus
Target
-