PAK7 antibody (AA 600-700)

Catalog No. ABIN7269143

The Rabbit Polyclonal anti-PAK7 antibody has been validated for WB. It is suitable to detect PAK7 in samples from Human.

Quick Overview for PAK7 antibody (AA 600-700) (ABIN7269143)

Target: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAK7 Antibody

Binding Specificity: AA 600-700

Purpose: PAK5 Rabbit pAb

Sequence: RKSLVGTPYW MAPEVISRLP YGTEVDIWSL GIMVIEMIDG EPPYFNEPPL QAMRRIRDSL PPRVKDLHKV SSVLRGFLDL MLVREPSQRA TAQELLGHPF L

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 600-700 of human PAK5 (NP_065074.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PAK7

Target: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Alternative Name: PAK5

Background: The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.,PAK5,PAK7,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,TGF-b-Smad Signaling Pathway,Neuroscience,PAK5

Molecular Weight: 80kDa

Gene ID: 57144

UniProt: Q9P286