PCNT antibody
Quick Overview for PCNT antibody (ABIN7269216)
Target
See all PCNT AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- PCNT Rabbit pAb
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Cross-Reactivity
- Human, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of human PCNT.
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Isotype
- IgG
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Application Notes
- WB,1:1000 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- PCNT (Pericentrin (PCNT))
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Alternative Name
- PCNT
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Background
- The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene.,KEN, PCN, MOPD2, PCNT2, PCNTB, PCTN2, SCKL4,PCNT
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Molecular Weight
- 378kDa
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Gene ID
- 5116
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UniProt
- O95613
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Pathways
- Sensory Perception of Sound, M Phase, SARS-CoV-2 Protein Interactome
Target
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