PHF8 antibody

Catalog No. ABIN7269263

The Rabbit Monoclonal anti-PHF8 antibody is suitable to detect PHF8 in samples from Human. It has been validated for WB.

Quick Overview for PHF8 antibody (ABIN7269263)

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PHF8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHF8 Antibody

Purpose: PHF8 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human PHF8

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PHF8

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Alternative Name: PHF8

Background: The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010],JHDM1F, KDM7B, MRXSSD, ZNF422,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Demethylation,Epigenetics & Nuclear Signaling,PHF8

Molecular Weight: 140kDa

Gene ID: 23133

UniProt: Q9UPP1