PDE10A antibody (AA 23-200)

Catalog No. ABIN7269297

This anti-PDE10A antibody is a Rabbit Polyclonal antibody detecting PDE10A in WB. Suitable for Human.

Quick Overview for PDE10A antibody (AA 23-200) (ABIN7269297)

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE10A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE10A Antibody

Binding Specificity: AA 23-200

Purpose: PDE10A Rabbit pAb

Sequence: SLTDEKVKAY LSLHPQVLDE FVSESVSAET VEKWLKRKNN KSEDESAPKE VSRYQDTNMQ GVVYELNSYI EQRLDTGGDN QLLLYELSSI IKIATKADGF ALYFLGECNN SLCIFTPPGI KEGKPRLIPA GPITQGTTVS AYVAKSRKTL LVEDILGDER FPRGTGLESG TRIQSVLC

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-200 of human PDE10A (NP_001124162.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDE10A

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Alternative Name: PDE10A

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.,PDE10A,ADSD2,HSPDE10A,IOLOD,LINC00473,PDE10A19,PDE10A

Molecular Weight: 88kDa/89kDa

Gene ID: 10846

UniProt: Q9Y233

Pathways: cAMP Metabolic Process