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PDE10A Antibodies

(phosphodiesterase 10A (PDE10A))
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011].
PDE10A antibody PDE10A antibody PDE10A antibody (ABIN2728471)

PDE10A Reactivity: Human IHC, WB Host: Mouse Monoclonal 1B2 unconjugated

PDE10A antibody  (AA 508-779) PDE10A antibody  (AA 508-779) PDE10A antibody (AA 508-779) (ABIN7436099)

PDE10A Reactivity: Human ICC, IHC, IP, WB Host: Rabbit Polyclonal unconjugated

PDE10A antibody  (N-Term) PDE10A antibody  (N-Term) PDE10A antibody (N-Term) (ABIN6264085)

PDE10A Reactivity: Human, Mouse ELISA, ICC, IF, WB Host: Rabbit Polyclonal unconjugated

PDE10A Antibodies by Reactivity

Find PDE10A Antibodies for a variety of species such as anti-Human PDE10A, anti-Mouse PDE10A, anti-Rat PDE10A. The species listed below are among those available. Click on a link to go to the corresponding products.

PDE10A Antibodies by Application

Find PDE10A Antibodies validated for a specific application such as WB, ELISA, IP, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PDE10A Antibodies by Host

Find PDE10A Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

PDE10A Antibodies by Binding Specificity

Find PDE10A Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PDE10A Antibodies by Clonality

Find available monoclonal or polyclonal PDE10A Antibodies. Click on a link to go to the corresponding products.

PDE10A Antibodies by Clone

Find PDE10A Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

PDE10A Antibodies by Conjugate

Find PDE10A Antibodies with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PDE10A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (1)
  • (3)
Cat. No. ABIN2728471
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
  • (2)
Cat. No. ABIN7436099
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, ICC, IF, WB
Validations
  • (2)
Cat. No. ABIN6264085
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7269297
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, WB
Validations
  • (2)
Cat. No. ABIN1500071
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application CM, ICC, IF, IP, IHC, ELISA, WB
Validations
  • (12)
Cat. No. ABIN2747045
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application FACS, IF
Validations
  • (2)
Cat. No. ABIN2728472
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN3186358
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IP, IHC, WB
Validations
  • (1)
Cat. No. ABIN341169
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (p), IP, WB
Validations
  • (1)
Cat. No. ABIN1042642
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN564713
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN524248
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
Cat. No. ABIN6753822
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN2148600
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
Cat. No. ABIN2148599
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PDE10A Antibodies

Maréchal, Guillemette, Goupil, Blondin, Leclerc, Richard: "Cyclic nucleotide phosphodiesterases in human spermatozoa and seminal fluid: Presence of an active PDE10A in human spermatozoa." in: Biochimica et biophysica acta, Vol. 1861, Issue 2, pp. 147-156, (2017) (PubMed).

Goupil, Maréchal, El Hajj, Tremblay, Richard, Leclerc: "Identification and Localization of the Cyclic Nucleotide Phosphodiesterase 10A in Bovine Testis and Mature Spermatozoa." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161035, (2016) (PubMed).

Li, Lee, Xi, Zhu, Gary, Ramírez-Alcántara, Gurpinar, Canzoneri, Fajardo, Sigler, Piazza, Chen, Andrews, Thomas, Lu, Li, Laan, Moyer, Russo, Eberhardt, Yet, Keeton, Grizzle, Piazza: "Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity." in: Oncogene, Vol. 34, Issue 12, pp. 1499-509, (2015) (PubMed).

Harada, Suzuki, Miura, Hasui, Kamiguchi, Ishii, Taniguchi, Kuroita, Takano, Stepanov, Halldin, Kimura: "Characterization of the binding properties of T-773 as a PET radioligand for phosphodiesterase 10A." in: Nuclear medicine and biology, Vol. 42, Issue 2, pp. 146-54, (2015) (PubMed).

Sancesario, Morrone, DAngelo, Castelli, Ferrazzoli, Sica, Martorana, Sorge, Cavaliere, Bernardi, Giorgi: "Levodopa-induced dyskinesias are associated with transient down-regulation of cAMP and cGMP in the caudate-putamen of hemiparkinsonian rats: reduced synthesis or increased catabolism?" in: Neurochemistry international, Vol. 79, pp. 44-56, (2015) (PubMed).

Mango, Bonito-Oliva, Ledonne, Nisticò, Castelli, Giorgi, Sancesario, Fisone, Berretta, Mercuri: "Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions." in: Neuropharmacology, Vol. 76 Pt A, pp. 127-36, (2014) (PubMed).

Heine, Sygnecka, Scherf, Berndt, Egerland, Hage, Franke: "Phosphodiesterase 2 inhibitors promote axonal outgrowth in organotypic slice co-cultures." in: Neuro-Signals, Vol. 21, Issue 3-4, pp. 197-212, (2013) (PubMed).

Tian, Vroom, Ghofrani, Weissmann, Bieniek, Grimminger, Seeger, Schermuly, Pullamsetti: "Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling." in: PLoS ONE, Vol. 6, Issue 4, pp. e18136, (2011) (PubMed).

Giorgi, Melchiorri, Nuccetelli, DAngelo, Martorana, Sorge, Castelli, Bernardi, Sancesario: "PDE10A and PDE10A-dependent cAMP catabolism are dysregulated oppositely in striatum and nucleus accumbens after lesion of midbrain dopamine neurons in rat: a key step in parkinsonism physiopathology." in: Neurobiology of disease, Vol. 43, Issue 1, pp. 293-303, (2011) (PubMed).

Ong, Gribble, Reimann, Lynch, Houslay, Baillie, Furman, Pyne: "The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon-like peptide-1 release." in: British journal of pharmacology, Vol. 157, Issue 4, pp. 633-44, (2009) (PubMed).

Aliases for PDE10A Antibodies

phosphodiesterase 10A (PDE10A) Antibodies
phosphodiesterase 10A (Pde10a) Antibodies
HSPDE10A Antibodies
Pde10a3 Antibodies
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