PFKL antibody (AA 700-780)

Catalog No. ABIN7269308

The Rabbit Polyclonal anti-PFKL antibody has been validated for WB and IF. It is suitable to detect PFKL in samples from Human.

Quick Overview for PFKL antibody (AA 700-780) (ABIN7269308)

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKL antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PFKL Antibody

Binding Specificity: AA 700-780

Purpose: PFKL Rabbit pAb

Sequence: FANAPDSACV IGLKKKAVAF SPVTELKKDT DFEHRMPREQ WWLSLRLMLK MLAQYRISMA AYVSGELEHV TRRTLSMDKG F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 700-780 of human PFKL (NP_002617.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PFKL

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Alternative Name: PFKL

Background: This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants.,PFKL,ATP-PFK,PFK-B,PFK-L,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,PFKL

Molecular Weight: 85kDa/90kDa

Gene ID: 5211

UniProt: P17858

Pathways: Negative Regulation of Hormone Secretion, Warburg Effect