PGAM5 antibody (AA 30-225)

Catalog No. ABIN7269317

The Rabbit Polyclonal anti-PGAM5 antibody is suitable to detect PGAM5 in samples from Human. It has been validated for IHC and WB.

Quick Overview for PGAM5 antibody (AA 30-225) (ABIN7269317)

Target: PGAM5 (Phosphoglycerate Mutase Family Member 5 (PGAM5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGAM5 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-PGAM5 Antibody

Binding Specificity: AA 30-225

Purpose: PGAM5 Rabbit pAb

Sequence: KPRAGGDAEP RPAEPPAWAG GARPGPGVWD PNWDRREPLS LINVRKRNVE SGEEELASKL DHYKAKATRH IFLIRHSQYH VDGSLEKDRT LTPLGREQAE LTGLRLASLG LKFNKIVHSS MTRAIETTDI ISRHLPGVCK VSTDLLREGA PIEPDPPVSH WKPEAVQYYE DGARIEAAFR NYIHRADARQ EEDSYE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-225 of human PGAM5 (NP_612642.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PGAM5

Target: PGAM5 (Phosphoglycerate Mutase Family Member 5 (PGAM5))

Alternative Name: PGAM5

Background: Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.,PGAM5,BXLBV68,Signal Transduction,PGAM5

Molecular Weight: 28kDa/32kDa

Gene ID: 192111

UniProt: Q96HS1