Phospholipase D4 antibody (AA 52-200)

Catalog No. ABIN7269353

The Rabbit Polyclonal anti-Phospholipase D4 antibody is suitable to detect Phospholipase D4 in samples from Human. It has been validated for WB.

Quick Overview for Phospholipase D4 antibody (AA 52-200) (ABIN7269353)

Target: Phospholipase D4 (PLD4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase D4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Phospholipase D4 Antibody

Binding Specificity: AA 52-200

Purpose: PLD4 Rabbit pAb

Sequence: WQVPRPPTWG QVQPKDVPRS WEHGSSPAWE PLEAEARQQR DSCQLVLVES IPQDLPSAAG SPSAQPLGQA WLQLLDTAQE SVHVASYYWS LTGPDIGVND SSSQLGEALL QKLQQLLGRN ISLAVATSSP TLARTSTDLQ VLAARGAHV

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 52-200 of human PLD4 (NP_620145.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Phospholipase D4

Target: Phospholipase D4 (PLD4)

Alternative Name: PLD4

Background: 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA. Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor. Involved in phagocytosis of activated microglia.,PLD4,C14orf175,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Hydrolysis,Lipases,Cardiovascular,Lipids,PLD4

Molecular Weight: 55kDa

Gene ID: 122618

UniProt: Q96BZ4