PKM1-Specific antibody

Catalog No. ABIN7269383

The Rabbit Polyclonal anti-PKM1-Specific antibody is suitable to detect PKM1-Specific in samples from Human. It has been validated for IF, IHC and WB.

Quick Overview for PKM1-Specific antibody (ABIN7269383)

Target: PKM1-Specific

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Product Details

Purpose: PKM1-specific Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human PKM1-specific.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: PKM1-Specific

Background: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.,PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,PKM1-specific

Molecular Weight: 56kDa/57kDa/58kDa

Gene ID: 5315

UniProt: P14618