PABP antibody (AA 350-450)

Catalog No. ABIN7269446

The Rabbit Polyclonal anti-PABP antibody has been validated for WB, IHC and IF. It is suitable to detect PABP in samples from Human.

Quick Overview for PABP antibody (AA 350-450) (ABIN7269446)

Target: PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PABP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PABP Antibody

Binding Specificity: AA 350-450

Purpose: pAbPC1 Rabbit pAb

Sequence: VTEMNGRIVA TKPLYVALAQ RKEERQAHLT NQYMQRMASV RAVPNPVINP YQPAPPSGYF MAAIPQTQNR AAYYPPSQIA QLRPSPRWTA QGARPHPFQN M

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PABPC1 (NP_002559.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PABP

Target: PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

Alternative Name: PABPC1

Background: This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation, it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.,PABPC1,PAB1,PABP,PABP1,PABPC2,PABPL1,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,Regulation of eIF4 and p70 S6 Kinase,PABPC1

Molecular Weight: 61kDa/70kDa

Gene ID: 26986

UniProt: P11940

Pathways: SARS-CoV-2 Protein Interactome