PRDM12 antibody (AA 100-330)

Catalog No. ABIN7269498

Product Details anti-PRDM12 Antibody

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Binding Specificity: AA 100-330

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRDM12 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: PRDM12 Rabbit pAb

Sequence: LGIFSKTWIK AGTEMGPFTG RVIAPEHVDI CKNNNLMWEV FNEDGTVRYF IDASQEDHRS WMTYIKCARN EQEQNLEVVQ IGTSIFYKAI EMIPPDQELL VWYGNSHNTF LGIPGVPGLE EDQKKNKHED FHPADSAAGP AGRMRCVICH RGFNSRSNLR SHMRIHTLDK PFVCRFCNRR FSQSSTLRNH VRLHTGERPY KCQVCQSAYS QLAGLRAHQK SARHRPPSTA L

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-330 of human PRDM12 (NP_067632.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRDM12

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Alternative Name: PRDM12 (PRDM12 Products)

Synonyms: PRDM12 antibody, prdm12 antibody, MGC146714 antibody, PFM9 antibody, pfm9 antibody, Gm998 antibody, PR/SET domain 12 antibody, PR domain containing 12 antibody, PR domain containing 12 L homeolog antibody, PR domain containing 12a antibody, PRDM12 antibody, prdm12 antibody, prdm12.L antibody, Prdm12 antibody, prdm12a antibody

Background: This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017],HSAN8;PFM9;PRDM12,Epigenetics & Nuclear Signaling,PRDM12

Gene ID: 59335

UniProt: Q9H4Q4