P2RY12 antibody (C-Term)

Catalog No. ABIN7269751

This Rabbit Polyclonal antibody specifically detects P2RY12 in WB. It exhibits reactivity toward Human.

Quick Overview for P2RY12 antibody (C-Term) (ABIN7269751)

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-P2RY12 Antibody

Binding Specificity: C-Term

Purpose: P2RY12 Rabbit pAb

Sequence: INFLIVIVCY TLITKELYRS YVRTRGVGKV PRKKVNVKVF IIIAVFFICF VPFHFARIPY TLSQTRDVFD CTAENTLFYV KESTLWLTSL NACLDPFIYF FLCKSFRNSL ISMLKCPNSA TSLSQDNRKK EQDGGDPNEE TPM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human P2RY12 (NP_795345.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for P2RY12

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Alternative Name: P2RY12

Background: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.,P2RY12,ADPG-R,BDPLT8,HORK3,P2T(AC),P2Y(12)R,P2Y(AC),P2Y(ADP),P2Y(cyc),P2Y12,SP1999,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,P2RY12

Molecular Weight: 39kDa

Gene ID: 64805

UniProt: Q9H244