CDK5RAP3 antibody (AA 51-150) (HRP)

Catalog No. ABIN717485

The Rabbit Polyclonal anti-CDK5RAP3 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect CDK5RAP3 in samples from Human.

Quick Overview for CDK5RAP3 antibody (AA 51-150) (HRP) (ABIN717485)

Target: CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK5RAP3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CDK5RAP3 Antibody (HRP)

Binding Specificity: AA 51-150

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDK5RAP3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CDK5RAP3

Target: CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))

Alternative Name: CDK5RAP3

Background:

Synonyms: C53, CDK5 activator binding protein C53, CDK5 regulatory subunit associated protein 3, HSF 27, HSF27, IC53, Ischemic heart CDK5 activator binding protein C53, LXXLL/leucine zipper containing ARFbinding protein, LZAP, MST016, OK/SW cl.114, PP1553, CK5P3_HUMAN.

Background: Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation.

Gene ID: 80279