ARHGDIA antibody

Catalog No. ABIN7269962

The Rabbit Monoclonal anti-ARHGDIA antibody is suitable to detect ARHGDIA in samples from Human. It has been validated for WB.

Quick Overview for ARHGDIA antibody (ABIN7269962)

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ARHGDIA antibody is un-conjugated

Application: Western Blotting (WB)

Grade: KO Validated

Product Details anti-ARHGDIA Antibody

Purpose: [KO Validated] RhoGDI Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human RhoGDI

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGDIA

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Alternative Name: ARHGDIA

Background: This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],GDIA1, HEL-S-47e, NPHS8, RHOGDI, RHOGDI-1,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,G protein signaling,G protein signaling_Small G proteins,Signal Transduction,ARHGDIA

Molecular Weight: 26kDa

Gene ID: 396

UniProt: P52565

Pathways: Neurotrophin Signaling Pathway