Rho-related GTP-binding protein antibody (C-Term)
Quick Overview for Rho-related GTP-binding protein antibody (C-Term) (ABIN7269975)
Target
See all Rho-related GTP-binding protein (RhO (pan)) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purpose
- Rhodopsin Rabbit pAb
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Sequence
- NESFVIYMFV VHFTIPMIII FFCYGQLVFT VKEAAAQQQE SATTQKAEKE VTRMVIIMVI AFLICWVPYA SVAFYIFTHQ GSNFGPIFMT IPAFFAKSAA IYNPVIYIMM NKQFRNCMLT TICCGKNPLG DDEASATVSK TETSQVAPA
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Cross-Reactivity
- Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human Rhodopsindopsin (NP_000530.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Rho-related GTP-binding protein (RhO (pan))
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Alternative Name
- RHO
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Background
- Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.,RHO,CSNBAD1,OPN2,RP4,rhodopsin,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,RHO
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Molecular Weight
- 38kDa
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Gene ID
- 6010
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UniProt
- P08100
Target
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