RBM8A antibody

Catalog No. ABIN7270089

This anti-RBM8A antibody is a Rabbit Monoclonal antibody detecting RBM8A in WB. Suitable for Human.

Quick Overview for RBM8A antibody (ABIN7270089)

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RBM8A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RBM8A Antibody

Purpose: Y14/RBM8A Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Y14/RBM8A

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RBM8A

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Alternative Name: RBM8A

Background: This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B, it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013],BOV-1A, BOV-1B, BOV-1C, C1DELq21.1, DEL1q21.1, MDS014, RBM8, RBM8B, TAR, Y14, ZNRP, ZRNP1,Epigenetics & Nuclear Signaling,RBM8A

Molecular Weight: 19kDa

Gene ID: 9939

UniProt: Q9Y5S9