SEC61B antibody (AA 1-96)

Catalog No. ABIN7270173

The Rabbit Polyclonal anti-SEC61B antibody (ABIN7270173) specifically detects SEC61B in WB and IF. The antibody is reactive with Human samples.

Quick Overview for SEC61B antibody (AA 1-96) (ABIN7270173)

Target: SEC61B (Sec61 beta Subunit (SEC61B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC61B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Grade: KO Validated

Product Details anti-SEC61B Antibody

Binding Specificity: AA 1-96

Purpose: [KO Validated] SEC61B Rabbit pAb

Sequence: MPGPTPSGTN VGSSGRSPSK AVAARAAGST VRQRKNASCG TRSAGRTTSA GTGGMWRFYT EDSPGLKVGP VPVLVMSLLF IASVFMLHIW GKYTRS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-96 of human SEC61B (NP_006799.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SEC61B

Target: SEC61B (Sec61 beta Subunit (SEC61B))

Alternative Name: SEC61B

Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.,SEC61B,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,SEC61B

Molecular Weight: 9kDa

Gene ID: 10952

UniProt: P60468

Pathways: Protein targeting to Nucleus