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SEC61B antibody (AA 1-96)
KO Validated
SEC61B
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SEC61B Antibody
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Target
See all SEC61B Antibodies
SEC61B
(Sec61 beta Subunit (SEC61B))
Binding Specificity
All epitopes for SEC61B antibodies
AA 1-96
Reactivity
All reactivities for SEC61B antibodies
Human
Host
All hosts for SEC61B antibodies
Rabbit
Clonality
All clonalities for SEC61B antibodies
Polyclonal
Conjugate
All conjugates for SEC61B antibodies
This SEC61B antibody is un-conjugated
Application
All applications for SEC61B antibodies
Western Blotting (WB), Immunofluorescence (IF)
Purpose
[KO Validated] SEC61B Rabbit pAb
Sequence
MPGPTPSGTN VGSSGRSPSK AVAARAAGST VRQRKNASCG TRSAGRTTSA GTGGMWRFYT EDSPGLKVGP VPVLVMSLLF IASVFMLHIW GKYTRS
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Grade
KO Validated
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-96 of human SEC61B (NP_006799.1).
Isotype
IgG
Top Product
Discover our top product SEC61B Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for SEC61B
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Target
SEC61B
(Sec61 beta Subunit (SEC61B))
Alternative Name
SEC61B (SEC61B Products )
Synonyms
1190006C12Rik antibody, AI326121 antibody, AW122942 antibody, Sec61 translocon beta subunit antibody, Sec61 beta subunit antibody, SEC61B antibody, Sec61b antibody
Background
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.,SEC61B,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,SEC61B
Molecular Weight
9kDa
Gene ID
10952
UniProt
P60468
Pathways
Protein targeting to Nucleus
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