SELM antibody (AA 50-130)

Catalog No. ABIN7270195

This Rabbit Polyclonal antibody specifically detects SELM in WB. It exhibits reactivity toward Human.

Quick Overview for SELM antibody (AA 50-130) (ABIN7270195)

Target: SELM (Selenoprotein M (SELM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SELM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SELM Antibody

Binding Specificity: AA 50-130

Purpose: SELENOM Rabbit pAb

Sequence: LNRLKEVKAF VTQDIPFYHN LVMKHLPGAD PELVLLGRRY EELERIPLSE MTREEINALV QELGFYRKAA PDAQVPPEYV W

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human SELENOM (NP_536355.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SELM

Target: SELM (Selenoprotein M (SELM))

Alternative Name: SELENOM

Background: The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.,SELENOM;SELM;SEPM,SELENOM

Molecular Weight: 16kDa

Gene ID: 140606

UniProt: Q8WWX9