SPINK5 antibody
Quick Overview for SPINK5 antibody (ABIN7270212)
Target
See all SPINK5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- SPINK5 / LEKTI Rabbit mAb
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of Human SPINK5 / LEKTI.
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- SPINK5 (serine Peptidase Inhibitor, Kazal Type 5 (SPINK5))
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Alternative Name
- SPINK5 / LEKTI
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Background
- This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants.,SPINK5,LEKTI,LETKI,NETS,NS,VAKTI,Cell Biology & Developmental Biology,Ubiquitin,Cardiovascular,Angiogenesis,SPINK5 / LEKTI
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Molecular Weight
- 104kDa/120kDa/124kDa
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Gene ID
- 11005
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UniProt
- Q9NQ38
Target
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