SLC7A8 antibody (AA 150-250)

Catalog No. ABIN7270479

Product Details anti-SLC7A8 Antibody

Target: SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Binding Specificity: AA 150-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC7A8 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: SLC7A8 Rabbit pAb

Sequence: LFPTCFPPES GLRLLAAICL LLLTWVNCSS VRWATRVQDI FTAGKLLALA LIIIMGIVQI CKGEYFWLEP KNAFENFQEP DIGLVALAFL QGSFAYGGWN F

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC7A8 (NP_036376.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLC7A8

Target: SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Alternative Name: SLC7A8 (SLC7A8 Products)

Background: Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (reabsorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.,SLC7A8,LAT2,LPI-PC1,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,SLC7A8

Molecular Weight: 34kDa/37kDa/48kDa/58kDa

Gene ID: 23428

UniProt: Q9UHI5