TXNDC3/NME8 antibody (AA 299-588)

Catalog No. ABIN7270801

This Rabbit Polyclonal antibody specifically detects TXNDC3/NME8 in WB. It exhibits reactivity toward Human.

Quick Overview for TXNDC3/NME8 antibody (AA 299-588) (ABIN7270801)

Target: TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNDC3/NME8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TXNDC3/NME8 Antibody

Binding Specificity: AA 299-588

Purpose: NME8 Rabbit pAb

Sequence: FMDAFFPDFK KMKSMKLEKT LALLRPNLFH ERKDDVLRII KDEDFKILEQ RQVVLSEKEA QALCKEYENE DYFNKLIENM TSGPSLALVL LRDNGLQYWK QLLGPRTVEE AIEYFPESLC AQFAMDSLPV NQLYGSDSLE TAEREIQHFF PLQSTLGLIK PHATSEQREQ ILKIVKEAGF DLTQVKKMFL TPEQIEKIYP KVTGKDFYKD LLEMLSVGPS MVMILTKWNA VAEWRRLMGP TDPEEAKLLS PDSIRAQFGI SKLKNIVHGA SNAYEAKEVV NRLFEDPEEN

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 299-588 of human NME8 (NP_057700.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TXNDC3/NME8

Target: TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))

Alternative Name: NME8

Background: This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.,NME8,CILD6,HEL-S-99,NM23-H8,SPTRX2,TXNDC3,sptrx-2,NME8

Molecular Weight: 67kDa

Gene ID: 51314

UniProt: Q8N427

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis