TMX1 antibody (AA 210-280)

Catalog No. ABIN7270808

The Rabbit Polyclonal anti-TMX1 antibody is suitable to detect TMX1 in samples from Human. It has been validated for WB and IHC.

Quick Overview for TMX1 antibody (AA 210-280) (ABIN7270808)

Target: TMX1 (Thioredoxin-Related Transmembrane Protein 1 (TMX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TMX1 Antibody

Binding Specificity: AA 210-280

Purpose: TMX1 Rabbit pAb

Sequence: KRRRPQPYPY PSKKLLSESA QPLKKVEEEQ EADEEDVSEE EAESKEGTNK DFPQNAIRQR SLGPSLATDK S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-280 of human TMX1 (NP_110382.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TMX1

Target: TMX1 (Thioredoxin-Related Transmembrane Protein 1 (TMX1))

Alternative Name: TMX1

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides.,TMX1,PDIA11,TMX,TXNDC,TXNDC1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,TMX1

Molecular Weight: 31kDa

Gene ID: 81542

UniProt: Q9H3N1

Pathways: Cell RedoxHomeostasis