TLR6 antibody (AA 32-200)

Catalog No. ABIN7270847

The Rabbit Polyclonal anti-TLR6 antibody has been validated for WB and IF. It is suitable to detect TLR6 in samples from Human.

Quick Overview for TLR6 antibody (AA 32-200) (ABIN7270847)

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-TLR6 Antibody

Binding Specificity: AA 32-200

Purpose: TLR6 Rabbit pAb

Sequence: NEFAVDKSKR GLIHVPKDLP LKTKVLDMSQ NYIAELQVSD MSFLSELTVL RLSHNRIQLL DLSVFKFNQD LEYLDLSHNQ LQKISCHPIV SFRHLDLSFN DFKALPICKE FGNLSQLNFL GLSAMKLQKL DLLPIAHLHL SYILLDLRNY YIKENETESL QILNAKTLH

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 32-200 of human TLR6 (NP_006059.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TLR6

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Alternative Name: TLR6

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.,TLR6,CD286,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,TLR6

Molecular Weight: 55kDa/91kDa

Gene ID: 10333

UniProt: Q9Y2C9

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades