TRIM62 antibody (AA 120-280)

Catalog No. ABIN7270996

Product Details anti-TRIM62 Antibody

Target: TRIM62 (Tripartite Motif Containing 62 (TRIM62))

Binding Specificity: AA 120-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM62 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: TRIM62 Rabbit pAb

Sequence: HEQHQVTGID DAFDELQREL KDQLQALQDS EREHTEALQL LKRQLAETKS STKSLRTTIG EAFERLHRLL RERQKAMLEE LEADTARTLT DIEQKVQRYS QQLRKVQEGA QILQERLAET DRHTFLAGVA SLSERLKGKI HETNLTYEDF PTSKYTGPLQ Y

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human TRIM62 (NP_060677.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIM62

Target: TRIM62 (Tripartite Motif Containing 62 (TRIM62))

Alternative Name: TRIM62 (TRIM62 Products)

Synonyms: TRIM62 antibody, trim62 antibody, MGC115263 antibody, dear1 antibody, DEAR1 antibody, zgc:158653 antibody, 6330414G21Rik antibody, AI450348 antibody, tripartite motif containing 62 antibody, tripartite motif containing 62 L homeolog antibody, tripartite motif-containing 62 antibody, TRIM62 antibody, trim62.L antibody, trim62 antibody, Trim62 antibody

Background: E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C-type lectin receptors, leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways. E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.,TRIM62,DEAR1,Cell Biology & Developmental Biology,TRIM62

Molecular Weight: 40kDa/54kDa

Gene ID: 55223

UniProt: Q9BVG3