USP47 antibody (AA 1128-1287)

Catalog No. ABIN7271166

This anti-USP47 antibody is a Rabbit Polyclonal antibody detecting USP47 in WB and IHC. Suitable for Human.

Quick Overview for USP47 antibody (AA 1128-1287) (ABIN7271166)

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP47 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-USP47 Antibody

Binding Specificity: AA 1128-1287

Purpose: USP47 Rabbit pAb

Sequence: VEKMKSMSQL AVLSRRWKPS EMKLDPFQEV VLESSSVDEL REKLSEISGI PLDDIEFAKG RGTFPCDISV LDIHQDLDWN PKVSTLNVWP LYICDDGAVI FYRDKTEELM ELTDEQRNEL MKKESSRLQK TGHRVTYSPR KEKALKIYLD GAPNKDLTQD

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1128-1287 of human USP47 (NP_060414.3).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for USP47

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Alternative Name: USP47

Background: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB, stabilizing POLB thereby playing a role in base-excision repair (BER. Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.,USP47,TRFP,Cell Biology & Developmental Biology,Ubiquitin,USP47

Molecular Weight: 18kDa/147kDa/154kDa/157kDa

Gene ID: 55031

UniProt: Q96K76

Pathways: Negative Regulation of intrinsic apoptotic Signaling