UBA3 antibody
Quick Overview for UBA3 antibody (ABIN7271186)
Target
See all UBA3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- UBA3 Rabbit mAb
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of Human UBA3.
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
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Alternative Name
- UBA3
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Background
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,UBA3,NAE2,UBE1C,hUBA3,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,UBA3
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Molecular Weight
- 50kDa/51kDa
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Gene ID
- 9039
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UniProt
- Q8TBC4
Target
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