B4GALT2 antibody (AA 155-271)

Catalog No. ABIN7271198

The Rabbit Polyclonal anti-B4GALT2 antibody is suitable to detect B4GALT2 in samples from Human. It has been validated for WB and IHC.

Quick Overview for B4GALT2 antibody (AA 155-271) (ABIN7271198)

Target: B4GALT2 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 2 (B4GALT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B4GALT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-B4GALT2 Antibody

Binding Specificity: AA 155-271

Purpose: B4GALT2 Rabbit pAb

Sequence: PGVLMGGRYT PPDCTPAQTV AVIIPFRHRE HHLRYWLHYL HPILRRQRLR YGVYVINQHG EDTFNRAKLL NVGFLEALKE DAAYDCFIFS DVDLVPMDDR NLYRCGDQPR HFAIAMD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 155-271 of human B4GALT2 (NP_085076.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for B4GALT2

Target: B4GALT2 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 2 (B4GALT2))

Alternative Name: B4GALT2

Background: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],B4Gal-T2,B4Gal-T3,beta4Gal-T2,B4GALT2,B4GALT2

Gene ID: 8704

UniProt: O60909

Pathways: Glycosaminoglycan Metabolic Process