Strumpellin antibody (AA 380-530)

Catalog No. ABIN7271349

This anti-Strumpellin antibody is a Rabbit Polyclonal antibody detecting Strumpellin in WB and IHC. Suitable for Human.

Quick Overview for Strumpellin antibody (AA 380-530) (ABIN7271349)

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Strumpellin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Strumpellin Antibody

Binding Specificity: AA 380-530

Purpose: KIAA0196 Rabbit pAb

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 380-530 of human KIAA0196 (NP_055661.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Strumpellin

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Alternative Name: KIAA0196

Background: This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease, a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts. More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases.,RTSC, SPG8, RTSC1, KIAA0196,KIAA0196

Gene ID: 9897

UniProt: Q12768