Strumpellin antibody (C-Term)

Catalog No. ABIN1450091

The Rabbit Polyclonal anti-Strumpellin antibody is suitable to detect Strumpellin in samples from Human, Mouse and Rat. It has been validated for WB and EIA.

Quick Overview for Strumpellin antibody (C-Term) (ABIN1450091)

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Strumpellin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Strumpellin Antibody

Binding Specificity: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: A 19 amino acid synthetic peptide near the carboxy terminus of Human Strumpellin

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Strumpellin

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Alternative Name: Strumpellin

Background: Strumpellin is a ubiquitously expressed, multi-transmembrane and spectrin-repeat-containing protein. It is named for Strumpell disease, a progressive upper-motor neurodegenerative disease termed hereditary spastic paraplegia (HSP). The Strumpellin gene maps to the eighth HSP locus (SPG8) on chromosome 8p24.13. Three families liked to this locus have mutations in the Strumpellin gene, rescue studies of zebrafish with decreased Strumpellin expression with Strumpellin mRNA containing these mutations showed impaired normal function of this protein. Recent studies suggest that Strumpellin may also be involved in protein aggregation diseases.Synonyms: KIAA0196

Gene ID: 9897

NCBI Accession: NP_055661