IL7R antibody

Catalog No. ABIN7271839

This Mouse Monoclonal antibody specifically detects IL7R in FACS. It exhibits reactivity toward Human.

Quick Overview for IL7R antibody (ABIN7271839)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: 4G8

Product Details anti-IL7R Antibody

Purpose: CD127 Unconjugated Antibody

Characteristics: The clone 4G8, a mouse monoclonal antibody selectively recognizes a 60-90 kDa surface type 1 transmembrane glycoprotein antigen known as CD127 or IL-7 receptor α chain (IL-7Rα). CD127 forms a heterodimer with the common γ chain of the receptors of several cytokines such as IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. It is widely expressed on different subsets of B cells, peripheral T cells and bone marrow stromal cells. CD127 plays important role in the generation of memory and effector T cells as well as functional B cells.

Purification: Purified

Purity: >95 %

Immunogen: Purified homodimeric form of T-ALL mutant and monomeric WT hIL-7Ralpha conjugated KLH

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: CD127

Gene ID: 3575

UniProt: P16871

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size