CD166 antibody

Catalog No. ABIN7271843

The Mouse Monoclonal anti-CD166 antibody is suitable to detect CD166 in samples from Human. It has been validated for FACS.

Quick Overview for CD166 antibody (ABIN7271843)

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD166 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: 3A6

Product Details anti-CD166 Antibody

Purpose: CD166 Unconjugated Antibody

Characteristics: The clone 3A6, a mouse monoclonal antibody, recognizes a ~100 kD transmembrane glycoprotein domain known as CD166 (the CD6 ligand) or the Activated Leukocyte Cell Adhesion Molecule (ALCAM). CD166 belongs to the immunoglobulin superfamily (IgSF) and it is widely expressed on activated lymphocytes and monocytes as well as other non-hematopoietic cells such as epithelial cells, fibroblasts and nerve cells. CD166 plays various roles in mediating physiological processes including angiogenesis, immune response and cell migration during the neuronal develop-ment. Overexpression of CD166 contributes positive indication of MM progression and that purified soluble CD166 effectively inhibits tumor progression. CD166 might be a potential therapeutic target against hematopoietic malignancy including MM.

Purification: Purified

Purity: >95 %

Immunogen: Cultured human thymic epithelial cells

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD166

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Alternative Name: CD166

Gene ID: 214

UniProt: Q13740