DENND4C antibody (PE)

Catalog No. ABIN7272069

The PE-conjugated Mouse Monoclonal anti-DENND4C antibody (Clone 3E8) (ABIN7272069) specifically detects DENND4C in WB, ICC, IF and IP. The antibody is reactive with Human samples.

Quick Overview for DENND4C antibody (PE) (ABIN7272069)

Target: DENND4C (DENN/MADD Domain Containing 4C (DENND4C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DENND4C antibody is conjugated to PE

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 3E8

Product Details anti-DENND4C Antibody (PE)

Purpose: Mouse Anti-Human DENND4C Monoclonal IgG1,

Specificity: Widely expressed,Detects ~213 kDa.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G Purified

Immunogen: Full Length Human Recombinant Dennd4c protein

Isotype: IgG1

Application Details

Application Notes: WB (1:1000), optimal dilutions for assays should be determined by the user.

Comment:

A 1:1000 dilution was sufficient for detection of DENND4C in A549, MEF cells by Western Blot analysis.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for DENND4C

Target: DENND4C (DENN/MADD Domain Containing 4C (DENND4C))

Alternative Name: DENND4C

Background: Dennd4c is a guanine nucleotide exchange factor (GEF) for Rab10, and required for GLUT4 translocation (1). It is associated with Alkuraya-Kucinskas Syndrome and Koolen-De Vries Syndrome (2) and interacts with the retromer (3)., cellular localisation: Cell membrane , Cytoplasm , Cytoplasmic vesicle , Membrane

Gene ID: 55667

NCBI Accession: NM_017925

UniProt: Q5VZ89