EEF1E1 antibody

Catalog No. ABIN7384097

This Rabbit Polyclonal antibody specifically detects EEF1E1 in WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for EEF1E1 antibody (ABIN7384097)

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EEF1E1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-EEF1E1 Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human EEF1E1 (NP_004271.1).

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EEF1E1

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Alternative Name: EEF1E1

Background: EEF1E1,AIMP3,P18,This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Molecular Weight:

Observed_MW: 20 kDa

Calculated_MW: 15 kDa/19 kDa

Gene ID: 9521

UniProt: O43324

Pathways: Positive Regulation of Response to DNA Damage Stimulus