EEF1E1 antibody (AA 1-100)
Quick Overview for EEF1E1 antibody (AA 1-100) (ABIN7267023)
Target
See all EEF1E1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-100
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Purpose
- EEF1E1 Rabbit pAb
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Sequence
- MAAAAELSLL EKSLGLSKGN KYSAQGERQI PVLQTNNGPS LTGLTTIAAH LVKQANKEYL LGSTAEEKAI VQQWLEYRVT QVDGHSSKND IHTLLKDLNS
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EEF1E1 (NP_004271.1).
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Isotype
- IgG
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Application Notes
- WB,1:200 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
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Alternative Name
- EEF1E1
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Background
- This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.,EEF1E1,AIMP3,P18,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,EEF1E1
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Molecular Weight
- 15kDa/19kDa
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Gene ID
- 9521
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UniProt
- O43324
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Target
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