GRP78 antibody

Catalog No. ABIN7384357

This anti-GRP78 antibody is a Rabbit Monoclonal antibody detecting GRP78 in WB and IHC (p). Suitable for Human and Rat.

Quick Overview for GRP78 antibody (ABIN7384357)

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GRP78 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R03-5B3

Product Details anti-GRP78 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GRP78

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Alternative Name: GRP78 BiP

Background: 78 kDa glucose regulated protein,78 kDa glucose-regulated protein,AL022860,AU019543,BIP,D2Wsu141e,D2Wsu17e,Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78,Endoplasmic reticulum lumenal Ca2+ binding protein grp78,Epididymis secretory sperm binding protein Li 89n,FLJ26106,Glucose Regulated Protein 78 kDa,GRP 78,GRP-78,GRP78,GRP78,Heat shock 70 kDa protein 5,Heat Shock 70 kDa Protein 5,Heat shock protein family A (Hsp70) member 5,HEL S 89n,Hsce70,HSPA 5,HSPA5,Immunoglobulin Heavy Chain Binding Protein,Immunoglobulin heavy chain-binding protein,mBiP,MIF2,Sez7,The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.

Molecular Weight:

Observed_MW: 78kDa

Calculated_MW: 72kDa

Gene ID: 3309

UniProt: P11021

Pathways: Thyroid Hormone Synthesis, ER-Nucleus Signaling