Hexokinase 2 antibody

Catalog No. ABIN7384359

The Rabbit Monoclonal anti-Hexokinase 2 antibody has been validated for WB and IHC (p). It is suitable to detect Hexokinase 2 in samples from Human, Rat and Hamster.

Quick Overview for Hexokinase 2 antibody (ABIN7384359)

Target: Hexokinase 2 (HK2)

Reactivity: Human, Rat, Hamster

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Hexokinase 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R06-4F4

Product Details anti-Hexokinase 2 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Hexokinase 2

Target: Hexokinase 2 (HK2)

Alternative Name: Hexokinase II

Background: DKFZp686M1669,Hexokinase 2,Hexokinase 2 muscle,Hexokinase type II,Hexokinase-2,HK 2,HK II,HK2,HKII,HxK 2,HxK2,HXK2,Muscle form hexokinase,Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Molecular Weight:

Observed_MW: 102kDa

Calculated_MW: 102kDa

Gene ID: 3099

UniProt: P52789

Pathways: PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect