MAPK14 antibody

Catalog No. ABIN7384365

The Rabbit Monoclonal anti-MAPK14 antibody has been validated for WB. It is suitable to detect MAPK14 in samples from Human, Rat and Hamster.

Quick Overview for MAPK14 antibody (ABIN7384365)

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Reactivity: Human, Rat, Hamster

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MAPK14 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: R06-6C0

Product Details anti-MAPK14 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAPK14

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Alternative Name: p38

Background: CSAID Binding Protein 1,CSAID binding protein,CSAID-binding protein,Csaids binding protein,CSBP 1,CSBP 2,CSBP,CSBP1,CSBP2,CSPB1,Cytokine suppressive anti-inflammatory drug-binding protein,EXIP,MAP kinase 14,MAP kinase MXI2,MAP kinase p38 alpha,MAPK 14,MAPK14,MAX interacting protein 2,MAX-interacting protein 2,Mitogen Activated Protein Kinase 14,Mitogen activated protein kinase p38 alpha,Mitogen-activated protein kinase 14,Mitogen-activated protein kinase p38 alpha,MK14,Mxi 2,MXI2,p38 ALPHA,p38,p38 MAP kinase,p38 MAPK,p38 mitogen activated protein kinase,p38ALPHA,p38alpha Exip,PRKM14,PRKM15,RK,SAPK2A,MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A,p38MAPK,CSBP1,RK,p38,EXIP,Mxi2,CSBP2,PRKM14,PRKM15,CSPB1,p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation. It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell. This protein has 4 isoforms produced by alternative splicing.

Molecular Weight:

Observed_MW: 41kDa

Calculated_MW: 41kDa

Gene ID: 1432

UniProt: Q16539

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins