SEMA4D/CD100 antibody

Catalog No. ABIN7384370

This Rabbit Monoclonal antibody specifically detects SEMA4D/CD100 in WB. It exhibits reactivity toward Human.

Quick Overview for SEMA4D/CD100 antibody (ABIN7384370)

Target: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SEMA4D/CD100 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: R05-2E3

Product Details anti-SEMA4D/CD100 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SEMA4D/CD100

Target: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Alternative Name: Semaphorin 4D

Background: A8,BB 18,BB18,CD 100,CD100,CD100 antigen,Coll 4,COLL4,Collapsin 4,Collapsin4,GR3,Leukocyte activation antigen CD100,M sema G,MSEMA,SEM4D,Sema 4d,Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D,Sema H,SEMA J,Sema4d,Semacl 2,Semacl2,SemaH,SEMAJ,Semaphorin 4D,Semaphorin C like 2,Semaphorin H,Semaphorin J,Semaphorin-4D,Semaphorin4D,SemaphorinJ,Semcl 2,Semcl2,Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system, induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

Molecular Weight:

Observed_MW: 120kDa

Calculated_MW: 96kDa

Gene ID: 10507

UniProt: Q92854

Pathways: Regulation of Cell Size