NAMPT antibody

Catalog No. ABIN7384400

This Rabbit Monoclonal antibody specifically detects NAMPT in WB and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for NAMPT antibody (ABIN7384400)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NAMPT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R05-4C4

Product Details anti-NAMPT Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Alternative Name: Nampt

Background: 1110035O14Rik,AI314458,AI480535,DKFZP666B131,EC 2.4.2.12,MGC117256,NAmPRTase,Nampt,NAMPT,Nicotinamide phosphoribosyltransferase,PBEF 1,PBEF,PBEF1,Pre B cell colony enhancing factor 1,Pre B cell colony enhancing factor,Pre B cell enhancing factor,Pre-B cell-enhancing factor,Pre-B-cell colony-enhancing factor 1,VF,Visfatin,Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide,an intermediate in the biosynthesis of NAD,which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow,liver tissue,and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus (T2DM),and it is now evidenced that NAMPT may plays a role in lipid metabolism.

Molecular Weight:

Observed_MW: 56kDa

Calculated_MW: 56kDa

Gene ID: 10135

UniProt: P43490