Calsyntenin 1 antibody

Catalog No. ABIN7384432

This anti-Calsyntenin 1 antibody is a Rabbit Monoclonal antibody detecting Calsyntenin 1 in WB and IHC (p). Suitable for Human, Mouse and Hamster.

Quick Overview for Calsyntenin 1 antibody (ABIN7384432)

Target: Calsyntenin 1 (CLSTN1)

Reactivity: Human, Mouse, Hamster

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Calsyntenin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R07-8H2

Product Details anti-Calsyntenin 1 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Calsyntenin 1

Target: Calsyntenin 1 (CLSTN1)

Alternative Name: CLSTN1

Background: CST-1,CSTN1,CDHR12,PIK3CD,ALC-ALPHA,XB31alpha,alcalpha1,alcalpha2,Calsyntenins (calsyntenin-1, -2, -3) compose a family of neuronally expressed proteins that belong to the cadherin superfamily of cell adhesion molecules (PMID: 24966372, 12498782). Calsyntenin-1 (CLSTN1) is a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain. By binding Ca2+, calsyntenin-1 may modulate Ca2+-mediated postsynaptic signals (PMID: 11161476). Calsyntenin-1 is a transmembrane cargo-docking protein for Kinesin-1-mediated vesicular transport (PMID: 16760430). It can mediate axonal transport of the amyloid precursor protein and regulate Aβ production

Molecular Weight:

Observed_MW: 110kDa

Calculated_MW: 110kDa

Gene ID: 22883

UniProt: O94985