Glutathione Reductase antibody

Catalog No. ABIN7384447

This anti-Glutathione Reductase antibody is a Rabbit Monoclonal antibody detecting Glutathione Reductase in WB. Suitable for Human.

Quick Overview for Glutathione Reductase antibody (ABIN7384447)

Target: Glutathione Reductase (GSR)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Glutathione Reductase antibody is un-conjugated

Application: Western Blotting (WB)

Clone: R08-2E4

Product Details anti-Glutathione Reductase Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Glutathione Reductase

Target: Glutathione Reductase (GSR)

Alternative Name: Glutathione Reductase

Background: GLR1,GLUR,Glutathione reductase,Glutathione reductase mitochondrial,Glutathione reductase,mitochondrial,GR,Gr1,GRase,GRD 1,GRD1,GSHR,GSR,MGC78522,This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Molecular Weight:

Observed_MW: 51kDa

Calculated_MW: 56kDa

Gene ID: 2936

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis