MCM2 antibody
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- Target See all MCM2 Antibodies
- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This MCM2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purification
- Affinity Purified
- Clone
- R08-9H4
- Isotype
- IgG
- Top Product
- Discover our top product MCM2 Primary Antibody
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- Application Notes
- WB 1:500-1:1000 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Concentration
- 300 μg/mL
- Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
- Alternative Name
- MCM2 (MCM2 Products)
- Background
- BM28,CCNL 1,CCNL1,CDC like 1,cdc19,CDCL 1,CDCL1,Cell devision cycle like 1,Cyclin like 1,D3S3194,DNA replication licensing factor MCM2,KIAA0030,MCM 2,MCM2,MCM2 minichromosome maintenance deficient 2 mitotin,MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae),MCM2 minichromosome maintenance deficient 2,mitotin,MCM2,MGC10606,Minichromosome maintenance complex component 2,Minichromosome maintenance deficient 2 (mitotin),Minichromosome maintenance deficient 2 mitotin,Minichromosome maintenance protein 2,Minichromosome maintenance protein 2 homolog,Mitotin,Nuclear protein BM28,OTTHUMP00000216047,OTTHUMP00000216050,The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with mCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
- Molecular Weight
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Observed_MW: 125kDa
Calculated_MW: 102kDa
- Gene ID
- 4171
- UniProt
- P49736
- Pathways
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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