PRMT7 antibody

Catalog No. ABIN7384485

The Rabbit Monoclonal anti-PRMT7 antibody is suitable to detect PRMT7 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for PRMT7 antibody (ABIN7384485)

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PRMT7 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: R06-4F6

Product Details anti-PRMT7 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRMT7

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Alternative Name: PRMT7

Background: [Myelin basic protein]-arginine N-methyltransferase PRMT7,ANM7,FLJ10640,Histone-arginine N-methyltransferase PRMT7,KIAA1933,Myelin basic protein arginine N methyltransferase,OTTHUMP00000174863,PRMT7,Protein arginine methyltransferase 7,Protein arginine N-methyltransferase 7,Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene. Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).

Molecular Weight:

Observed_MW: 79kDa

Calculated_MW: 79kDa

Gene ID: 54496

UniProt: Q9NVM4

Pathways: Ribonucleoprotein Complex Subunit Organization