STING/TMEM173 antibody

Catalog No. ABIN7384500

The Rabbit Monoclonal anti-STING/TMEM173 antibody has been validated for WB and IHC (p). It is suitable to detect STING/TMEM173 in samples from Human and Rat.

Quick Overview for STING/TMEM173 antibody (ABIN7384500)

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This STING/TMEM173 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R06-9A7

Product Details anti-STING/TMEM173 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STING/TMEM173

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Alternative Name: Transmembrane Protein 173

Background: Endoplasmic reticulum IFN stimulator,Endoplasmic reticulum interferon stimulator,ERIS,FLJ38577,hMITA,hSTING,Mediator of IRF3 activation,MITA,Mitochondrial mediator of IRF3 activation,MPYS,N terminal methionine proline tyrosine serine plasma membrane tetraspanner,NET23,Stimulator of interferon genes,Stimulator of interferon genes protein,STING,TM173,Tmem173,Transmembrane protein 173,This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 40kDa

Calculated_MW: 42kDa

Gene ID: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response